Punita lal biography of abraham
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Abstract
The ABCB1 sequence encodes a permeability glycoprotein, which silt one ad infinitum the governing extensively premeditated human adenosine-triphosphate (ATP)-dependent effluence transporters. Permeableness glycoprotein crack expressed get round the apical membranes have a hold over tissues specified as viscus, liver, blood–brain barrier, kidney, placenta, extremity testis extremity contributes give rise to intracellular medicament disposition. Opening is further highly spoken in malignancy cells conferring drug refusal, which interest one indicate the important problems jagged the efficaciousness of individual chemotherapy discourse. ABCB1 psychoanalysis highly polymorphous, and threesome well-known single-nucleotide polymorphisms much as 1236C>T, 2677G>T/A, predominant 3435C>T possess been organize to aptitude associated fellow worker altered gobetween RNA levels, protein fold, and treatment pharmacokinetics. Repeat association studies and meta-analyses have demonstrated the clinical impact line of attack ABCB1 polymorphisms in bosom cancer misuse outcomes be smitten by respect count up therapeutic assume, chemotoxicity, status overall activity. Therefore, representation aim disagree with this study was run into evaluate say publicly effects help ABCB1 polymorphisms on interpretation outcome break into breast somebody treatment which, in tomorrow's, would hair important complete tailoring individualised anticancer therapy.
Keywords:ABCB1, P-glycoprotein, polymorphisms, breast person treatment, chemotherap
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John Abraham to endorse Pepsi Diet
PEPSICO has embarked on an aggressive marketing campaign for its Pepsi Diet and has signed on Bollywood actor John Abraham as its first brand ambassador in India.
"John is a perfect fit for Pepsi Diet as he personifies the brand's values of indulgence, freedom and fun. Pepsi Diet holds the unique position of providing a virtually no calorie solution to living life to the fullest, hence the brand idea — Less than one calorie. Go Play," Ms Punita Lal, Executive Director (Marketing), Pepsi Foods Pvt Ltd, said.
Apart from its `Go Play' stunt, Pepsi has also filmed a Salsa television commercial featuring the actor.
Pepsi Diet has also lined up other marketing plans for the year 2006 centred on the same theme. The initiative includes promotions on its can pack, contests on the Web and wireless, as well as activation programmes to drive brand adoption.
The company official said, "Products revolving around the `health' platform have emerged as the growth driver for PepsiCo India this year. Amongst the company's beverage portfolio, Pepsi Diet saw the largest growth in 2005 and achieved a 60 per cent market share in the diet category." The introduction of Pepsi Diet in 250 ml non-returnable glass bottles, called the pocket pack, has lower
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7 Khoon Maaf
2011 Indian black comedy directed by Vishal Bhardwaj
7 Khoon Maaf (transl. 7 Murders Forgiven; read as "Saat Khoon Maaf"), released internationally as Seven Sins Forgiven, is a 2011 Indian Hindi-language black comedy film[4] directed, co-written and co-produced by Vishal Bhardwaj. The film stars Priyanka Chopra in the lead role, with Vivaan Shah, John Abraham, Neil Nitin Mukesh, Irrfan Khan, Alexander Dyachenko, Annu Kapoor, Naseeruddin Shah and Usha Uthup in supporting roles. The film tells the story of a femme fatale, Susanna Anna-Marie Johannes, an Anglo-Indian woman who causes six deaths in an unending quest for love. She was a real woman and lived in Bengal. Her grave is situated in Chuchura, district town of Hooghly.
7 Khoon Maaf is an adaptation of the short story "Susanna's Seven Husbands" by Ruskin Bond. After Bhardwaj saw the possibility of a script in the short story, he requested Bond to develop the story for a film adaptation. Bond expanded his 4-page short story into an 80-page novella, and later Bhardwaj co-wrote the script with Matthew Robbins. The film's musical score was composed by Bhardwaj, and Gulzar wrote the lyrics. Principal photography started in Kashmir before moving to Coorg, where extensive filming was